Endocrine Abstracts

VEGF (vascular endothelial growth factor) is an endothelial cell mitogen responsible for physiological and pathophysiological angiogenesis. Abnormal regulation of VEGF expression in anterior pituitary folliculostellate (FS) cells has been implicated in pituitary tumour progression. PACAP is a well-documented stimulant of VEGF secretion from the pituitary in which both FS and endocrine cells express VEGF. TtT/GF cells are a mouse pituitary cell line with many characteristics of...